Each Espin H 5/12.5 mg tablet contains Amlodipine (Espin H) 5 mg equivalent to Amlodipine (Espin H) besilate 6.934 mg and Hydrochlorothiazide (Espin H) 12.5 mg.
Each Espin H 10/12.5 mg tablet contains Amlodipine (Espin H) 10 mg equivalent to Amlodipine (Espin H) besilate 13.868 mg and Hydrochlorothiazide (Espin H) 12.5 mg.
Prescription: Yes
Medicine Interaction: If you use other drugs or over the counter products at the same time, the effects of Espin H Tablet may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Espin H Tablet may interact with the following drugs and products:
Alcohol, Aspirin, Atorvastatin, Cholestyramine, Cimetidine, Colestipol, Corticosteroids, Cyclosporine, Digitalis Glycosides, Digoxin.
Drug Schedule: Schedule H & G Prescription Drug
Side Effects: Nervous System: Hypertonia, hypoesthesia, paresthesia, peripheral neuropathy, tremor, insomnia, mood changes, somnolence, dizziness, headache, vertigo, nervousness, depression, abnormal dreams, anxiety, depersonalization.
Cardiovascular: Hypotension, syncope, vasculitis, palpitations, myocardial infarction, arrhythmia (including ventricular tachycardia and atrial fibrillation), tachycardia, flushing, edema, chest pain, peripheral ischemia, postural dizziness, postural hypotension.
Gastrointestinal: Dry mouth, thirst, altered bowel habits, dyspepsia, gastritis, gingival hyperplasia, pacreatitis, Nausea, vomiting, abdominal pain, constipation, dysphagia, diarrhea, flatulence.
Endocrine/Metabolic: Gynecomastia, hyperglycemia, impotence, increased/decreased weight, anorexia.
Hematological: Purpura, thrombocytopenia, leukopenia.
Skin and Appendages: Increased sweating, alopecia, skin discoloration, urticaria, allergic reactions including pruritus, rash, angioedema, and erythema multiforme, purpura.
Urogenital/Reproductive: Increased urinary frequency, micturition disorder, nocturia.
Hepatic: Hepatitis, jaundice, hepatic enzyme elevations.
Musculoskeletal: Arthralgia, arthrosis, muscle cramps, myalgia, back pain.
Respiratory: Coughing, dyspnea, rhinitis, epistaxis.
Special Senses: Taste perversion, tinnitus, visual disturbances, abnormal vision, conjunctivitis, diplopia, eye pain.
Hydrochlorothiazide (Espin H): Body as a Whole: Fever, fatigue, weakness.
Nervous System: Insomnia, cephalalgia, dizziness, restlessness, vertigo, paresthesia, headache.
Cardiovascular: Hypotension including orthostatic hypotension (may be aggravated by alcohol, barbiturates, narcotics, antihypertensive drugs), transient cerebral ischemic attacks.
Gastrointestinal: Sialadenitis, spasms, stomach irritation, Nausea, vomiting, diarrhea, constipation, pancreatitis, cramping, gastric irritation.
Endocrine/Metabolic: Anorexia, hyperglycemia, hyperuricemia, hypokalemia, hyponatremia, hypochloremic alkalosis, hypophosphatemia, hypomagnesemia, hypercalcemia, glucose tolerance impairment, glycosuria, increased total cholesterol, low density lipoprotein cholesterol (LDL-c), very low density lipoprotein cholesterol (VLDL-c) and triglycerides, impotence.
Hematologic: Agranulocytosis, aplastic anemia, hemolytic anemia, leukopenia, thrombocytopenia.
Skin and Appendages: Rash, erythema multiforme including Stevens-Johnson syndrome, exfoliative dermatitis including toxic epidermal necrolysis, alopecia, anaphylactic reaction, necrotizing angiitis (vasculitis, cutaneous vasculitis), purpura, urticaria, photosensitivity, polyarteritis nodosa.
Urogenital/Reproductive: Glycosuria, interstitial nephritis, renal dysfunction, failure and impairment.
Hepatic: Icterus (intrahepatic cholestatic jaundice).
Musculoskeletal: Muscle cramps and spasm.
Respiratory: Respiratory distress including pneumonitis and pulmonary edema.
Special Senses: Transient blurred vision, xanthopsia.
How to Store it: Store in a cool, dry and dark place
Over Dose: Store in a cool, dry and dark place
Precautions: Store in a cool, dry and dark place
Missed Dose: Store in a cool, dry and dark place
