Atenolol (Nilol) is a β1-selective adrenergic-blocking agent. It competitively blocks adrenergic stimulation of β1-adrenergic receptors within the myocardium and vascular smooth muscle. Low doses of Atenolol (Nilol) selectively inhibit cardiac and lipolytic β1-receptors but with little effect on the β2-adrenergic receptors of bronchial and vascular smooth muscle. At high doses (ie, >100 mg daily), this selectivity of Atenolol (Nilol) for β1-adrenergic receptors may diminish and the drug may competitively block β1- and β2-adrenergic receptors. Atenolol (Nilol) does not exhibit any intrinsic sympathomimetic Activity nor any membrane-stabilizing Activity.
Prescription: Yes
Warnings: Do not use Nilol Tablet 10's if you are allergic to Nilol Tablet 10's or any of its components. Let your doctor know if you have any history of severe kidney or liver diseases, low potassium levels (hypokalaemia), chest pain (angina), poor blood circulation or controlled heart failure, first-degree heart block, diabetes, thyrotoxicosis (a condition caused by an overActive thyroid gland), liver problems, and adrenal gland diseases. Let your doctor know if you have anuria (kidneys aren't producing urine), fluid or electrolyte imbalance, lupus erythematosus (an autoimmune inflammatory disease-causing scaly red patches on the skin), gout, abnormal heart rhythms, thyroid disorders, and asthma before starting Nilol Tablet 10's. It is essential to let your doctor know if you are a breastfeeding mother before using Nilol Tablet 10's since Indapamide may pass into the breast milk. Please ask your doctor if you plan to conceive or are pregnant before using Nilol Tablet 10's. Nilol Tablet 10's can increase the chances of light-headedness so rise slowly if you are sitting/lying and avoid operating any machine or doing any work that needs mental alertness. Nilol Tablet 10's is not recommended in people less than 18 years of age.
Medicine Interaction: Nilol Tablet 10's is known to interact when taken with an anticancer drug (quinidine), antiepileptic medicine (phenytoin), anti TB drug (rifampicin), antibiotics (erythromycin), other blood pressure-lowering pills (chlorthalidone, ramipril, metoprolol, lisinopril, amlodipine, candesartan, baclofen, levodopa, clonidine) and anti-psychotic drugs (alprazolam, risperidone, amisulpride, pimozide), anti-HIV drug (nelfinavir, ritonavir, saquinavir or amprenavir), drugs used to treat insomnia or anxiety (Phenobarbital).
Drug Schedule: Schedule H Prescription Drug
Side Effects: Dizziness, headache, flushing, fatigue, GI disturbances, oedema. Hypersensitivity reactions including angioedema and urticaria. Obstructive airways disease. W/ Atenolol (Nilol): Postural hypotension, bradycardia, cold extremities, heart block, intermittent claudication, Raynaud’s phenomenon, paraesthesia, bronchospasm. Mood changes and deterioration of heart failure. Sleep disturbances, alopecia, thrombocytopenia, purpura, psoriasis form skin reactions, exacerbation of psoriasis, visual disturbances, psychoses, nightmares, dry mouth, elevations of transaminase levels, rarely, hepatic toxicity, hallucination. Skin rashes and dry eyes. W/ Nifedipine (Nilol): Tachycardia, hypersensitivity type jaundice, gingival hyperplasia, palpitations, paresthesia, skin reactions, myalgia, tremor, increased frequency of micturition, gynaecomastia, liver function disturbances, intra-hepatic cholestasis and marked fall in BP in dailysis patients w/ malignant HTN and hypovolaemia. Gravitational oedema, dyspnoea and agranulocytosis.
How to Store it: Store in a cool, dry and dark place.
Over Dose: Store in a cool, dry and dark place.
Precautions: Store in a cool, dry and dark place.
Missed Dose: Store in a cool, dry and dark place.
