It is a more potent statin which competitively inhibits the conversion of 3-hydroxy-3-methyl glutaryl coenzyme A (HMG CoA) to mevalonate. The drug exerts it`s action by specific inhibition of enzyme; 3-hydroxy-3-methyl glutaryl coenzyme A reductase (HMG CoA reductase) and reduces cholesterol synthesis up to 50% at therapeutic doses. This results in compensatory increase in low density lipoprotein (LDL) receptor expression in liver which ultimately leads to increased receptor mediated uptake and catabolism of intermediate density lipoprotein(IDL) and low density lipoprotein (LDL). It causes dose dependent lowering of LDL cholesterol and reduces hepatic synthesis of very low density lipoprotein (VLDL) and lowers plasma triglyceride levels. It also increases high density lipoprotein (HDL) levels. It also exerts antioxidant property.
Prescription: Yes
Warnings: Stator 10 Tablet 15's may cause a breakdown of skeletal muscle tissue, leading to kidney failure. This condition usually occurs in the elderly, people with kidney disease, and poorly controlled hypothyroidism (underActive thyroid). Stator 10 Tablet 15's should not be prescribed to children less than 10 years of age. You should contact a doctor before if you have had an allergic reaction to Stator 10 Tablet 15's, have liver problem (jaundice, liver cirrohosis), or kidney problems, pregnant or planning to get pregnant, breastfeeding, have severe lung disease, have a previous heart attack or stroke caused by bleeding in the brain, have hypothyroidism, drink more than 2 servings of alcohol per day and have a muscle disorder (fibromyalgia) and damaged muscle tissue (rhabdomyolysis).
Medicine Interaction: This medicine may have interaction with antibiotics (like cephalexin, tetracycline, gentamicin), antifungals (like miconazole, fluconazole, and ketoconazole), HIV medicines (like abacavir, retrovir, and tenofovir), hepatitis C medicines (like ribavirin, elbasvir), anti-arthritis pills (cyclosporin), heart rate-controlling pills (amiodarone) and anti-hypertensive drugs (like verapamil, diltiazem).
Drug Schedule: Schedule H Prescription Drug
Side Effects: 1.Headache
2.Dizziness
3.Insomnia
4.Alopecia
5.Anorexia
6.Abdominal discomfort
7.Heart burn
8.Abdominal pain
9.Nausea
10.Dyspepsia
11.Flatulence
12.Constipation
13.Abnormal liver function tests
14.Rash
15.Pruritus
16.Fatigue
17.Myositis
18.Chest pain
19.Impotence
20.Myopathy
21.Upper respiratory tract infections
How to Store it: Store protected from moisture at a temperature not exceeding 30 C.
Over Dose: Store protected from moisture at a temperature not exceeding 30 C.
Precautions: Store protected from moisture at a temperature not exceeding 30 C.
Missed Dose: Store protected from moisture at a temperature not exceeding 30 C.